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Some people have gone through this journey for treatment. The goal is to reduce endometriosis and prevent it from taking hold. Pain can begin. We need to suppress endometriosis and move on to an IVF protocol to increase the chances of implantation. I am currently pregnant. But everything ended earlier — I had given birth before. Embryo karyotypes are normal. A question for those who have pursued this path because of endometriosis: How many injections are usually prescribed? After the third and fourth injections, did the sensations disappear? I also felt nothing after the second. Honestly, it’s scary. And did you end up getting pregnant?
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Elena
Buserelin didn't shut me down after three injections, and my periods were regular. Only Relugolix was stopped, but it's an incredibly expensive medication. Now I'm taking Visanne; I'm finishing the second pack and experiencing side effects like breakthrough bleeding; nothing has reduced. After stopping, everything got even worse. Regarding Visanne, I'll finish the third pack and go for an ultrasound, but in my case everything is very sad. I've just put together a post; you can read it.

Wishing you luck and hoping everything works out.
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Tkachenko Zhenya
Elena At one time, buserelin was counterfeit. That's why it's no longer available—someone released a placebo. If, after the first injection, the cycle doesn't knock you out, this is one such case. A doctor told me about this incident. It knocked me out. Ultimately, I would like to have a child. IVF with embryo transfer would be better.
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Elena
Elena So everything will work out!!! They won't even grant me a visa.
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Natalya
There were three injections. After the second, things got really tough, and I was overwhelmed by hot flashes and other symptoms. Overall, it was very hard. A spontaneous pregnancy never happened. Only IVF helped, in a downregulation protocol with the same Buserelin (one shot).
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Tkachenko Zhenya
Elena I hope you find a doctor who can help you.
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Tkachenko Zhenya
Natalya I think we should go straight to IVF. In the meantime, we’re on our way to the reproductive endocrinologist for the required assessment. I also have a tubal factor. Age and adenomyosis are factors.
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Natalya
Natalya Overall, while continuing the artificial-menopause protocol, proceed with the embryo transfer. For endometriosis, this is the most successful approach. The endometrium will be built up with Progynova, and so on; after that, progesterone will be started. It will be a fully artificial cycle, but in my case of advanced disease, this was the only thing that helped.
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Tkachenko Zhenya
Natalya I don't have any embryos yet. We're starting our first cycle now. After that, they'll be frozen for cryopreservation.
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Elena
Elena Unfortunately, there aren’t any like that yet. No one likes dealing with problematic patients, because our reputation could suffer. In fact, a leading reproductive endocrinologist told me directly at NGC: 'you’re too problematic; reputation is more important to us.'
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Tkachenko Zhenya
Elena There is an endometriosis clinic in Moniyag, Moscow. I am going there…
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